Hearts: (4-2-3-1) Beau Reus; Jordi Altena, Stuart Findlay, Jamie McCart, Harry Milne; Oisin McEntee, Laurent Mendy; Calvin Miller, Claudio Braga, Josh McPake; James Wilson.
Hearts boss Vrancken is unable to call on a handful of first-team players this week.
Craig Halkett, Tom Renaud, Blair Spittal and Finlay Pollock are injury absentees while Tomas Magnusson is suspended after his dismissal in the Conference League play-off at Rapid Vienna.
Miller, Braga and McPake should retain their places after all three scored in Saturday's win against St Mirren.
“It was very important to start well and get a result. The vibe is good and hopefully gives us more confidence and a vibe going forward.
“When we play a good game, I am always happy to see my team play well. “In and out of possession, we played a good game against St Mirren. “Hopefully, it gives every confidence to the next games that are coming.”
FC Nordsjaelland: (3-4-3) Andreas Hansen; Victor Nelsson, Tobias Salquist, Noah Markmann; Markus Walker, Justin Janssen, Mark Brink, Runar Norheim; Hjalte Boe Rasmussen, Villum Berthelsen, Ibrahim Adel.
Nordsjaelland boss Olsen could keep faith with much of the side that drew against Odense.
The visitors have a couple of injury issues this week with Araphat Mohammed and Souleymane Alio both expected to remain sidelined for the trip to Scotland.
Alexander Lind and Prince Amoako are in contention to earn recalls after appearing as second-half substitutes on Friday.